Safer prescribing · MICA
Prevent pregnancy exposure and plan an alternative.
Sources consulted 16 October 2026 · MICA scientific review to be confirmed
A major teratogen. The SmPC specifies two negative pregnancy tests before initiation, the second 8–10 days after the first; a defined exception concerns urgent deceased-donor transplantation. Breastfeeding is contraindicated in this SmPC. [1]
For women who may conceive: reliable contraception before, during and for 6 weeks after stopping; two methods are preferred. For sexually active men or their partners: reliable contraception during treatment and for at least 90 days afterwards, as a precaution. [2]
Contact the prescribing team immediately to arrange care. Pregnancy planning requires a compatible treatment strategy before conception. [1]
Personal reading prompts; no clinical data is recorded.
FICTIONAL LEARNING SCENARIO
Do paternal precautions prove the same risk as maternal exposure?
No. Maternal exposure is teratogenic; paternal precautions address a different uncertainty. [2]
Non-exhaustive adult learning guidance. Check indication, contraindications, product information and local context before an individual decision. Cited recommendations do not establish marketing authorisation in Algeria.