
Flash information
- Specimen
- Gastric mucosa
- Stain
- H&E
- Clue
- Ectasia and thrombi
- Presentation
- Anaemia or gastrointestinal bleeding
Definition
GAVE is a gastric vascular abnormality that may cause iron deficiency or gastrointestinal bleeding.
Examination or reading method
Identify tissue and stain; correlate dilated vessels with the pathology report and endoscopy.
Morphological description
The source describes dilated capillaries within the lamina propria and fibrin thrombi; this image is a histological section.
Causes and diagnostic direction
Associations with cirrhosis, systemic sclerosis and renal failure are reported; this section does not demonstrate them.
Differential diagnoses
Portal hypertensive gastropathy is a distinct entity; cirrhosis does not make these diagnoses interchangeable.
Associated findings
Assess iron-deficiency anaemia, melaena and transfusion requirements; document the endoscopic distribution of lesions.
Red flags
Overt bleeding with faintness or instability requires urgent assessment regardless of the histological image.
Pitfalls and limitations
A single section cannot map the disease or select haemostatic treatment; recurrence remains possible.
Take-home message
Link histology with endoscopy and monitor anaemia and bleeding; distinguish GAVE from portal gastropathy.
Sources
- Elhendawy M et al. Randomized controlled study of endoscopic band ligation and argon plasma coagulation in the treatment of gastric antral and fundal vascular ectasia. UEG J, 2016 ↗
- Eccles J et al. Long-term follow-up in patients with gastric antral vascular ectasia after treatment with endoscopic band ligation. Endosc Int Open, 2019 ↗
- Drinane M, Shah VH. Portal hypertensive gastropathy and gastric antral vascular ectasia. Complications of Cirrhosis, 2015;111–119(résumé institutionnel des auteurs, Mayo Clinic) ↗
Documentary review: 2026-10-15
Media source & rights
- Author
- Nephron
- Original source
- Nephron · Gastric antral vascular ectasia - high mag.jpg · CC BY-SA 3.0 · https://commons.wikimedia.org/wiki/File:Gastric_antral_vascular_ectasia_-_high_mag.jpg
- Licence
- CC BY-SA 3.0
- Changes
- Full original field and annotations retained; WebP conversion, EXIF/GPS metadata removed, proportional derivatives without upscaling, cropping or medical retouching. Derivatives shared under the same CC BY-SA 3.0 licence.
- Dimensions
- 4272 × 2848 px
- Check
- 2026-10-15