Original MICA image-reading exercise, unscored. No clinical narrative absent from the source is added.
- Describe visible findings before proposing an interpretation.
- Suggest an interpretation and at least one image limitation.
- Which clinical findings or investigations would complement this observation?
Reveal the explained reading
Membranous nephropathy: PAS stain
- Technique
- Histology
- Observation
- The stain highlights capillary walls.
- Limitation
- A single image cannot identify a specific antigen.
Morphological description
The stain highlights capillary walls.
Interpretation and diagnostic limits
Full interpretation requires several techniques.
Differential diagnoses
Consider other causes of capillary-wall thickening.
Pitfalls
A single image cannot identify a specific antigen.
Take-home message
One stain does not replace the complete biopsy.
Sources
Documentary review: 2026-10-15
Media source & rights
- Author
- Nephron
- Original source
- Nephron · Néphropathie membraneuse — coloration PAS · CC BY-SA 3.0
- Licence
- CC BY-SA 3.0
- Changes
- Full original field and annotations retained; WebP conversion, EXIF/GPS metadata removed, proportional derivatives without upscaling, cropping or medical retouching. Derivatives shared under the same CC BY-SA 3.0 licence.
- Dimensions
- 4272 × 2848 px
- Check
- 2026-10-15